Inflammation, Chronic Diseases and “Bone Quality”

Evolutionary medicine and bone loss in chronic inflammatory diseases--A theory of inflammation-related osteopenia.

OBJECTIVE Bone loss is typical in chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, ankylosing spondylitis, systemic lupus erythematosus, multiple sclerosis, inflammatory bowel diseases, pemphigus vulgaris, and others. It is also typical in transplantation-related inflammation and during the process of aging. While we recognized that bone loss is tightly linked to immune sy...

Diseases affecting bone quality: beyond osteoporosis.

BACKGROUND Bone quantity, quality, and turnover contribute to whole bone strength. Although bone mineral density, or bone quantity, is associated with increased fracture risk, less is known about bone quality. Various conditions, including disorders of mineral homeostasis, disorders in bone remodeling, collagen disorders, and drugs, affect bone quality. QUESTIONS/PURPOSES The objectives of th...

Food Insecurity and Chronic Diseases: The Editorial

Curcumin, inflammation, and chronic diseases: how are they linked?

It is extensively verified that continued oxidative stress and oxidative damage may lead to chronic inflammation, which in turn can mediate most chronic diseases including cancer, diabetes, cardiovascular, neurological, inflammatory bowel disease and pulmonary diseases. Curcumin, a yellow coloring agent extracted from turmeric, shows strong anti-oxidative and anti-inflammatory activities when u...

O 30: Peripheral Nervous System Diseases and Inflammation

Inflammatory neuropathies may be due to infection (with a specific casual agent identified) including Lyme disease, HIV, Leprosy, Herpes Zoster, Hepatitis B & C. The other group of are Autoimmune or possibly infectious (but with no specific causal infectious agent identified) including sarcoidosis, Guillain-Barre syndrome/ acute inflammatory demyelinating polyneuropathy ( AIDP), chronic in...